SCHEMBL2592201

SCHEMBL2592201

Nc1ccc(/N=N/c2cccc(S(=O)(=O)O)c2)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 7/20 1.00
SENP1 Q9P0U3 7/20 1.00
SENP3 Q9H4L4 5/20 1.00
SUMO2 P61956 4/20 1.00
SUMO1 P63165 4/20 1.00
SENP7 Q9BQF6 4/20 1.00
GLO1 Q04760 6/20 0.78
MAPT P10636 3/20 0.59
MAPK1 P28482 3/20 0.59
KMT2A Q03164 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
MEN1 O00255 2/20 0.59
NPC1 O15118 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
HSD17B10 Q99714 1/20 0.56
PHLPP2 Q6ZVD8 1/20 0.55
GAA P10253 2/20 0.53
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592202 1.00 SENP2 (1.00) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL29536781 1.00 SENP2 (1.00) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL15393681 0.95 SENP3 (0.90) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL12177914 0.94 SENP3 (0.88) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL12177942 0.92 SENP3 (0.85) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL12177911 0.92 SENP3 (0.85) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL2594013 0.91 SENP3 (0.83) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL2583416 0.91 SENP3 (0.83) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL2583414 0.91 SENP3 (0.83) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL2594010 0.91 SENP3 (0.83) SENP2SENP1SENP3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11041859-B2 Methods of identifying SENP1 inhibitors CITY OF HOPE (US) 2021-06-22 US disclosed
US-20180143196-A1 METHODS OF IDENTIFYING SENP1 INHIBITORS CITY OF HOPE 2018-05-24 US disclosed
US-9791447-B2 Methods of identifying SENP1 inhibitors CITY OF HOPE (US) 2017-10-17 US disclosed
EP-2566941-B1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2016-12-21 EP disclosed
EP-2566941-B1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2016-12-21 EP disclosed
US-20140302525-A1 METHODS OF IDENTIFYING SENP1 INHIBITORS CITY OF HOPE (US) 2014-10-09 US disclosed
US-8585780-B2 Dyes and blends for shading during laundry BASF SE (DE) 2013-11-19 US disclosed
US-20130247309-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-09-26 US disclosed
US-20130247309-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-09-26 US disclosed
EP-2566941-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-03-13 EP disclosed
WO-2011138183-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2011-11-10 WO disclosed
US-4399068-A Concentrated, aqueous solutions of salts of acetoacetylamino-arylsulphonic acids and method of forming concentrated solutions of azo dyestuffs therefrom BAYER AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed