Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659085 | 0.85 | POLB (0.39) | HPGDMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL17583023 | 0.85 | POLB (0.39) | HPGDMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL17583057 | 0.83 | HPGD (0.36) | NR3C1HPGDKCNQ2KCNQ3MEN1 | |
| SCHEMBL20110771 | 0.78 | POLB (0.38) | HPGDMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL21148132 | 0.76 | CSNK1D (0.33) | MAPTCSNK1D | |
| SCHEMBL21580986 | 0.73 | POLB (0.38) | HPGDMEN1KMT2AMAPTPOLB | |
| SCHEMBL17582768 | 0.72 | ALDH1A1 (0.34) | HPGDMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL20209791 | 0.72 | EGFR (0.34) | CSNK1DTSHR | |
| SCHEMBL16084486 | 0.71 | KCNQ2 (0.39) | NR3C1HPGDKCNQ2KCNQ3MEN1 | |
| SCHEMBL19276270 | 0.70 | KCNQ2 (0.39) | NR3C1HPGDKCNQ2KCNQ3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289822-A2 | BENZOIMIDAZOL-1,2-YL AMIDES AS KV7 CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-3572405-B1 | BENZOIMIDAZOL-1,2-YL AMIDES AS KV7 CHANNEL ACTIVATORS | KNOPP BIOSCIENCES LLC (US) | 2023-07-26 | — | — | EP | disclosed |