Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17583023 | 0.93 | POLB (0.39) | POLBPTGS2MEN1KMT2ATSHR | |
| SCHEMBL30659085 | 0.93 | POLB (0.39) | POLBPTGS2MEN1KMT2ATSHR | |
| SCHEMBL21580986 | 0.81 | POLB (0.38) | POLBPTGS2MEN1KMT2ATSHR | |
| SCHEMBL17582768 | 0.80 | ALDH1A1 (0.34) | POLBMEN1KMT2AHPGDHTT | |
| SCHEMBL17583068 | 0.78 | PTGS2 (0.46) | POLBPTGS2MEN1KMT2ATSHR | |
| SCHEMBL25922234 | 0.78 | NR3C1 (0.33) | POLBMEN1KMT2ATSHRHPGD | |
| SCHEMBL17583057 | 0.77 | HPGD (0.36) | MEN1KMT2AHPGDHTTNPSR1 | |
| SCHEMBL21148154 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL30659144 | 0.75 | MAPT (0.38) | POLBMEN1KMT2AHPGDHTT | |
| SCHEMBL17582767 | 0.75 | MAPT (0.38) | POLBMEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081825-A1 | BENZOIMIDAZOL-1, 2-YL AMIDES AS KV7 CHANNEL ACTIVATORS | KNOPP BIOSCIENCES LLC (US) | 2018-05-03 | — | — | WO | disclosed |