Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117140 | 1.00 | MAPT (0.46) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3127325 | 0.98 | MAPT (0.49) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3116277 | 0.98 | MAPT (0.49) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3431297 | 0.98 | MAPT (0.49) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3120777 | 0.94 | ALDH1A1 (0.40) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3116666 | 0.87 | — | — | |
| SCHEMBL25923287 | 0.83 | LTA4H (0.48) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL12564049 | 0.83 | LTA4H (0.48) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL2700161 | 0.83 | LTA4H (0.48) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL12153331 | 0.82 | CA1 (0.48) | ALDH1A1CA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | PDE9A, CGAS, PDE8A | MAPT 4750/4885ALDH1A1 3972/4885USP2 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.