Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317472 | 0.82 | TLR8 (0.42) | TLR8KDM1ATLR7EPRS1 | |
| SCHEMBL25923351 | 0.79 | TLR8 (0.38) | TLR8EPRS1 | |
| SCHEMBL25314887 | 0.79 | TLR8 (0.38) | TLR8EPRS1 | |
| SCHEMBL22172245 | 0.71 | HTT (0.37) | TLR8EPRS1 | |
| SCHEMBL25923371 | 0.71 | TLR8 (0.40) | TLR8TLR7 | |
| SCHEMBL25923353 | 0.64 | AR (0.40) | TLR8 | |
| SCHEMBL25316918 | 0.64 | AR (0.40) | TLR8 | |
| SCHEMBL25938341 | 0.64 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL25197710 | 0.62 | TLR8 (0.34) | TLR8TLR7 | |
| SCHEMBL25114046 | 0.61 | PDE4D (0.45) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |