Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759926 | 0.80 | KMT2A (0.61) | ALDH1A1KDM4ENR4A2MAPTKMT2A | |
| SCHEMBL29956558 | 0.76 | AHR (0.55) | ALDH1A1KDM4ESMN1; SMN2NR4A2MEN1 | |
| SCHEMBL1254486 | 0.76 | AHR (0.55) | ALDH1A1KDM4ESMN1; SMN2NR4A2MEN1 | |
| SCHEMBL4065612 | 0.74 | KDM4E (0.72) | ALDH1A1KDM4ESMN1; SMN2MAPK1MEN1 | |
| SCHEMBL5917605 | 0.73 | NR4A2 (0.69) | ALDH1A1KDM4ENR4A2MEN1KMT2A | |
| SCHEMBL670200 | 0.73 | AHR (0.57) | ALDH1A1KDM4ESMN1; SMN2MAPK1NR4A2 | |
| SCHEMBL28136136 | 0.73 | AHR (0.49) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL4208427 | 0.73 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPK1NR4A2 | |
| SCHEMBL7311550 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2MAPK1NR4A2 | |
| SCHEMBL1163942 | 0.72 | MAPT (0.55) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011139242-A2 | PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE DERIVATIVES | USTAV EXPIREMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) | 2011-11-10 | — | — | WO | disclosed |