SCHEMBL25924931

SCHEMBL25924931

CCN1CCC(N2CCC3(CCCN(I)C3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37
TLR9 Q9NR96 2/20 0.33
TLR7 Q9NYK1 2/20 0.33
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29329312 0.84 TSHR (0.40)
SCHEMBL27291235 0.83 KMT2A (0.41) KMT2ATLR9TLR7ACHE
SCHEMBL13180780 0.76 TSHR (0.39) KMT2A
SCHEMBL27267682 0.74 KMT2A (0.42) KMT2ATLR9TLR7ACHE
SCHEMBL2633490 0.74 POLB (0.37) KMT2ATLR7
SCHEMBL2633463 0.73 KMT2A (0.39) KMT2AACHE
SCHEMBL18551162 0.73 KMT2A (0.50) KMT2ATLR9TLR7ACHE
SCHEMBL20970888 0.73 TSHR (0.42)
SCHEMBL24235267 0.72 TSHR (0.41) KMT2A
SCHEMBL18202976 0.72 KMT2A (0.45) KMT2ATLR9TLR7ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109892-A1 COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 海思科医药集团股份有限公司 2023-06-22 WO disclosed