Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.31 |
| ▸ | USP2 | O75604 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924931 | 0.84 | KMT2A (0.37) | — | |
| SCHEMBL22851873 | 0.84 | TSHR (0.44) | TSHRKDM4EGAA | |
| SCHEMBL20970888 | 0.83 | TSHR (0.42) | TSHRCYP3A4USP2CYP2C19CYP2D6 | |
| SCHEMBL25090104 | 0.82 | TSHR (0.52) | TSHRCYP3A4USP2CYP2C19CYP2D6 | |
| SCHEMBL18938451 | 0.79 | USP2 (0.32) | TSHRCYP3A4USP2CYP2C19CYP2D6 | |
| SCHEMBL19046977 | 0.79 | GRM5 (0.31) | — | |
| SCHEMBL24919170 | 0.79 | — | — | |
| SCHEMBL18390933 | 0.78 | USP2 (0.49) | TSHRCYP3A4USP2CYP2C19CYP2D6 | |
| SCHEMBL20328047 | 0.78 | TSHR (0.52) | TSHR | |
| SCHEMBL29329315 | 0.78 | USP2 (0.36) | TSHRCYP3A4USP2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151346-A1 | HETEROARYL FLUOROALKENES AS DGK INHIBITORS | INCYTE CORPORATION (US) | 2024-07-18 | — | — | WO | disclosed |