Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19208198 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2XDHMEN1KMT2ATSHR | |
| SCHEMBL5148552 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPK1XDHKMT2AALDH1A1 | |
| SCHEMBL2888331 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1XDHMEN1KMT2A | |
| SCHEMBL14663783 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1XDHTSHRALDH1A1 | |
| SCHEMBL15656246 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2MAPK1MEN1KMT2ATSHR | |
| SCHEMBL20553301 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1XDHMEN1KMT2A | |
| SCHEMBL13024307 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1XDHMEN1KMT2A | |
| SCHEMBL24920108 | 0.74 | NPC1 (0.56) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL21847655 | 0.73 | ALDH1A1 (0.60) | SMN1; SMN2MAPK1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL28862024 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1XDHTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218578-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | C9, C5, C1QBP | SMN1; SMN2 2279/4885MAPK1 1424/4885XDH 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.