SCHEMBL259252

SCHEMBL259252

CC1OC1COC(=O)c1ccccc1C(=O)OCC1OC1C

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.53
ALDH1A1 P00352 8/20 0.50
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
CYP3A4 P08684 4/20 0.46
MAPK1 P28482 3/20 0.46
TP53 P04637 1/20 0.46
LMNA P02545 1/20 0.45
NPC1 O15118 1/20 0.44
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 1/20 0.40
CA2 P00918 1/20 0.40
CDC25B P30305 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9391130 0.94 ALDH1A1 (0.53) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL12959081 0.84 ALDH1A1 (0.57) TSHRALDH1A1TDP1MAPK1LMNA
SCHEMBL258991 0.81 HPGD (0.48) TSHRALDH1A1TDP1CYP3A4MAPK1
SCHEMBL28445075 0.79 DHFR (0.46) TSHRALDH1A1L3MBTL1TDP1CYP3A4
SCHEMBL9391084 0.76 MAPT (0.47) TSHRALDH1A1CYP3A4MAPK1TP53
SCHEMBL18474784 0.76 ALDH1A1 (0.52) TSHRALDH1A1TDP1MAPK1LMNA
SCHEMBL11178783 0.76 TSHR (0.46) TSHRALDH1A1L3MBTL1TDP1LMNA
SCHEMBL20691410 0.74 ALDH1A1 (0.51) TSHRALDH1A1TDP1MAPK1LMNA
SCHEMBL12886328 0.73 ALDH1A1 (0.50) TSHRALDH1A1TDP1MAPK1LMNA
SCHEMBL18508412 0.73 DHFR (0.50) TSHRL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7517943-B2 Golf ball layer compositions formed from oxirane functional endcapped polymers ACUSHNET COMPANY (US) 2009-04-14 US claimed
US-5552208-A High strength composite ALLIEDSIGNAL INC. (US) 1996-09-03 US claimed
US-20180243967-A1 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH, LTD. 2018-08-30 US disclosed
US-9979427-B2 Privacy and security systems and methods of use PPIP LLC (US) 2018-05-22 US disclosed
EP-3243160-A1 PRIVACY AND SECURITY SYSTEMS AND METHODS OF USE PPIP LLC (US) 2017-11-15 EP disclosed
US-20170284773-A9 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH LTD. (US) 2017-10-05 US disclosed
US-20170234657-A1 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH, LTD. 2017-08-17 US disclosed
WO-2016111728-A9 PRIVACY AND SECURITY SYSTEMS AND METHODS OF USE PPIP LLC (US) 2016-10-20 WO disclosed
EP-1585853-B1 BI-DIRECTIONAL AND MULTI-AXIAL FABRICS AND FABRIC COMPOSITES HONEYWELL INT INC (US) 2016-10-05 EP disclosed
US-20160234356-A1 PRIVACY AND SECURITY SYSTEMS AND METHODS OF USE PPIP LLC (US) 2016-08-11 US disclosed
US-20160233912-A1 PRIVACY AND SECURITY SYSTEMS AND METHODS OF USE PPIP LLC (US) 2016-08-11 US disclosed
US-4376173-A LIGNIN, CELLULOSE, POLYURETHANE FOAM, POLYISOCYANATE BLOUNT DAVID H 1983-03-08 US disclosed
US-4367326-A Process for the production of polyepoxy silicate resins DORSEY & WHITNEY LLP 1983-01-04 US disclosed
US-4292214-A LIGNIN-CELLULOSE EPOXY RESIN, POLYISOCYANATE BLOUNT DAVID H 1981-09-29 US disclosed
US-4292413-A Process for the production of epoxy cellular solid products BLOUNT DAVID H 1981-09-29 US disclosed
US-4235974-A Process for the production of epoxy cellular solid products BLOUNT DAVID H 1980-11-25 US disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed
US-4066625-A CURING AGENTS AMICON CORPORATION (US) 1978-01-03 US disclosed
US-4034014-A FROM MALEIC MONOMERS AND ALKYLSTYRENES ALLIED CHEMICAL CORPORATION (US) 1977-07-05 US disclosed