Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 14/20 | 0.41 |
| ▸ | BRD4 | O60885 | 13/20 | 0.41 |
| ▸ | BRD7 | Q9NPI1 | 8/20 | 0.41 |
| ▸ | BRD2 | P25440 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ATAD2B | Q9ULI0 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925594 | 0.88 | BRD9 (0.48) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25934791 | 0.86 | BRD9 (0.47) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25934789 | 0.84 | ERN1 (0.44) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25925604 | 0.77 | BRD9 (0.65) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25925479 | 0.73 | BRD9 (0.47) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25925475 | 0.73 | BRD9 (0.47) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25925473 | 0.71 | BRD4 (0.48) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL25925462 | 0.71 | BRD4 (0.48) | BRD9BRD4BRD7BRD2ERN1 | |
| SCHEMBL22305912 | 0.68 | BRD9 (0.61) | BRD9BRD4BRD7BRD2TAF1 | |
| SCHEMBL22290038 | 0.67 | BRD9 (0.60) | BRD9BRD4BRD7BRD2TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |