Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146311 | 0.82 | KMT2A (0.50) | CCR5KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL17502182 | 0.77 | HTT (0.41) | KMT2AMAPTTDP1KDM4EPOLB | |
| SCHEMBL15773977 | 0.74 | KMT2A (0.43) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL24502939 | 0.72 | KMT2A (0.41) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL12146972 | 0.72 | HSD17B10 (0.33) | CCR5KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL24369751 | 0.72 | OPRK1 (0.40) | CCR5KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL17688657 | 0.72 | LMNA (0.38) | KMT2AALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL2847704 | 0.72 | KMT2A (0.38) | KMT2AALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL30068918 | 0.71 | AURKA (0.47) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL857144 | 0.71 | AURKA (0.47) | KMT2AALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |