SCHEMBL25925890

SCHEMBL25925890

Cn1nccc1/N=N/c1cc(/N=N/c2ccc(S(N)(=O)=O)cc2)cc(O)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.49
PTGS1 P23219 5/20 0.49
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CASP6 P55212 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
ATM Q13315 1/20 0.46
KLF5 Q13887 1/20 0.46
CA2 P00918 7/20 0.46
CA1 P00915 4/20 0.46
CA12 O43570 6/20 0.46
CA9 Q16790 6/20 0.46
CA7 P43166 1/20 0.46
AMY1A P0DUB6 1/20 0.44
CYP1A2 P05177 3/20 0.43
CYP2C9 P11712 3/20 0.43
HSD17B10 Q99714 3/20 0.43
POLB P06746 3/20 0.43
MAPT P10636 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25925886 0.91 CA2 (0.51) PTGS2PTGS1MEN1KMT2ACASP6
SCHEMBL25925882 0.88 AHR (0.36) MEN1KMT2ANPC1RAB9AATM
SCHEMBL25925897 0.87 PTGS2 (0.51) PTGS2PTGS1MEN1KMT2ACASP6
SCHEMBL25925715 0.84 MEN1 (0.50) PTGS2PTGS1MEN1KMT2ACASP6
SCHEMBL25925718 0.84 MEN1 (0.50) PTGS2PTGS1MEN1KMT2ACASP6
SCHEMBL25925895 0.75 AHR (0.32) L3MBTL1
SCHEMBL25925933 0.74 PTGS1 (0.41) PTGS2PTGS1MEN1KMT2ANPC1
SCHEMBL25925862 0.72 MAPT (0.34) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL18250390 0.69 KMT2A (0.49) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL15049243 0.68 PTGS1 (0.46) PTGS2PTGS1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE AR, MAPT, NR5A1 PTGS2 3678/4885PTGS1 1753/4885MEN1 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.