Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723057 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL578753 | 0.88 | PDE3B (0.46) | ALDH1A1KMT2APDE3BPDE3AHPGD | |
| SCHEMBL24723273 | 0.81 | MAPT (0.47) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL25925369 | 0.80 | KMT2A (0.41) | ALDH1A1KMT2APDE3BPDE3AHPGD | |
| SCHEMBL22996784 | 0.77 | PDE3B (0.46) | ALDH1A1KMT2APDE3BPDE3AHPGD | |
| SCHEMBL27679680 | 0.76 | MAPK1 (0.44) | ALDH1A1KMT2APDE3BPDE3AHPGD | |
| SCHEMBL25926613 | 0.74 | KDM4E (0.42) | ALDH1A1KMT2APDE3BPDE3AMAPT | |
| SCHEMBL12989805 | 0.73 | ALDH1A1 (0.40) | ALDH1A1PDE3BPDE3AHPGDSMN1; SMN2 | |
| SCHEMBL29173633 | 0.72 | CA12 (0.47) | ALDH1A1KMT2APDE3BPDE3AHPGD | |
| SCHEMBL3759033 | 0.72 | CCR5 (0.42) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |