SCHEMBL25926328

SCHEMBL25926328

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3oc3cc(-c5ccc6c(c5)oc5c(-n7c8ccccc8c8ccccc87)cccc56)ccc34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 5/20 0.39
ALOX5 P09917 2/20 0.37
GGPS1 O95749 1/20 0.33
MAPT P10636 4/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CG P48736 1/20 0.32
KDM4E B2RXH2 3/20 0.32
TSHR P16473 3/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 3/20 0.32
POLB P06746 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25926337 0.96 PRKDC (0.39) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL24232711 0.96 PRKDC (0.39) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL25926319 0.96 PRKDC (0.42) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL21668992 0.96 PRKDC (0.42) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL25926282 0.96 PRKDC (0.42) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL24963164 0.95 PRKDC (0.36) PRKDCALOX5GGPS1MAPTKDM4E
SCHEMBL21740524 0.94 PRKDC (0.39) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL24216528 0.94 PRKDC (0.40) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL25926436 0.94 PRKDC (0.39) PRKDCALOX5GGPS1MAPTPIK3CD
SCHEMBL25701597 0.94 PRKDC (0.43) PRKDCALOX5GGPS1MAPTPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-08-03 US disclosed
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247902-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE CRY1, PPOX, ORC3 PRKDC 3471/4885ALOX5 959/4885GGPS1 415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.