Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601676 | 0.79 | MEN1 (0.49) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL29809554 | 0.79 | MEN1 (0.49) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL24225329 | 0.78 | KDM4E (0.43) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL13948718 | 0.75 | MEN1 (0.46) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL22166697 | 0.75 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL21391523 | 0.75 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL10273425 | 0.75 | GRM2 (0.43) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL4069129 | 0.75 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL20808748 | 0.73 | LMNA (0.46) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL30349755 | 0.72 | ALDH1A1 (0.40) | KMT2AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |