Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CCR4 | P51679 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055319 | 1.00 | SPHK1 (0.58) | SPHK1NPSR1CCR4SCN3AALDH1A1 | |
| SCHEMBL3399606 | 1.00 | SPHK1 (0.58) | SPHK1NPSR1CCR4SCN3AALDH1A1 | |
| SCHEMBL408685 | 0.89 | SPHK1 (0.71) | SPHK1NPSR1CCR4SCN3AMAOA | |
| SCHEMBL408684 | 0.89 | SPHK1 (0.71) | SPHK1NPSR1CCR4SCN3AMAOA | |
| SCHEMBL5154674 | 0.89 | SPHK1 (0.71) | SPHK1NPSR1CCR4SCN3AMAOA | |
| SCHEMBL2587055 | 0.89 | CYP1A2 (0.60) | SPHK1NPSR1CCR4CYP1A2OPRL1 | |
| SCHEMBL1972076 | 0.89 | CYP1A2 (0.60) | SPHK1NPSR1CCR4CYP1A2OPRL1 | |
| SCHEMBL27801286 | 0.89 | NPSR1 (0.57) | SPHK1NPSR1CCR4SCN3AALDH1A1 | |
| SCHEMBL1819248 | 0.89 | CYP1A2 (0.60) | SPHK1NPSR1CCR4CYP1A2OPRL1 | |
| Hydrochloric Acid SCHEMBL28533309 | 0.88 | SPHK1 (0.70) | SPHK1NPSR1CCR4SCN3AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138795-A2 | PROCESS FOR PREPARING (S)-10-ACETOXY-10,11-DIHYDRO-5H-DIBENZ[B,F] AZEPINE-5-CARBOXAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-11-10 | — | — | WO | claimed |
| US-20220127206-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| EP-3939954-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-01-19 | — | — | EP | disclosed |
| CN-113518771-A | Method for introducing deuterated lower alkyl into amine part of compound containing secondary amine | 大塚制药株式会社 | 2021-10-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127206-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | MGMT, FANCD2, ADAR | SPHK1 868/4885NPSR1 3935/4885CCR4 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.