SCHEMBL2592899

SCHEMBL2592899

Nc1ccc(/N=N/c2ccc(S(=O)(=O)O)cc2)c2cc(S(=O)(=O)O)ccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.73
CYP2C19 P33261 1/20 0.73
HSD17B10 Q99714 1/20 0.73
SENP2 Q9HC62 6/20 0.72
SENP3 Q9H4L4 5/20 0.72
SENP1 Q9P0U3 5/20 0.72
SUMO2 P61956 4/20 0.72
SUMO1 P63165 4/20 0.72
SENP7 Q9BQF6 4/20 0.72
PHLPP2 Q6ZVD8 2/20 0.71
SLC7A11 Q9UPY5 1/20 0.67
GLO1 Q04760 5/20 0.50
ENPP2 Q13822 1/20 0.49
RPS6KA3 P51812 1/20 0.49
POLB P06746 1/20 0.49
CYP2D6 P10635 1/20 0.49
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592902 1.00 CYP2C9 (0.73) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL12177917 0.99 CYP2C9 (0.75) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL12177913 0.96 CYP2C9 (0.79) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL2585430 0.94 CYP2C9 (0.81) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL2585427 0.94 CYP2C9 (0.81) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL12177962 0.92 PHLPP2 (0.84) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL12177954 0.92 SENP2 (0.77) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL8779986 0.92 SENP2 (0.77) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL15120312 0.92 SENP2 (0.72) CYP2C9CYP2C19HSD17B10SENP2SENP3
SCHEMBL14413264 0.91 CYP2C9 (0.88) CYP2C9CYP2C19HSD17B10SENP2SENP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2566941-B1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2016-12-21 EP disclosed
US-8585780-B2 Dyes and blends for shading during laundry BASF SE (DE) 2013-11-19 US disclosed
US-20130247309-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-09-26 US disclosed
EP-2566941-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2013-03-13 EP disclosed
WO-2011138183-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2011-11-10 WO disclosed
WO-2011138183-A1 DYES AND BLENDS FOR SHADING DURING LAUNDRY BASF SE (DE) 2011-11-10 WO disclosed
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-27 US disclosed
WO-2007006594-A2 REACTIVE AZO DYES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use IK, CYP1A1, ALKBH1 CYP2C9 13/4885CYP2C19 59/4885HSD17B10 1772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.