Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 6/20 | 0.49 |
| ▸ | HRH2 | P25021 | 5/20 | 0.48 |
| ▸ | HRH1 | P35367 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.46 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 4/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928642 | 0.88 | IP6K1 (0.45) | IP6K1HRH2HRH1DRD3IP6K3 | |
| SCHEMBL25316705 | 0.88 | IP6K1 (0.61) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30507360 | 0.88 | IP6K1 (0.61) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30507031 | 0.86 | IP6K1 (0.63) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25316240 | 0.86 | IP6K1 (0.63) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25317536 | 0.83 | HTR1A (0.49) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25315904 | 0.83 | HTR1A (0.46) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30507068 | 0.82 | IP6K1 (0.54) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25315886 | 0.82 | IP6K1 (0.54) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30506835 | 0.81 | HTR1A (0.44) | IP6K1ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |