Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 8/20 | 0.45 |
| ▸ | HRH2 | P25021 | 5/20 | 0.45 |
| ▸ | HRH1 | P35367 | 5/20 | 0.45 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25929422 | 0.88 | IP6K1 (0.49) | IP6K1HRH2HRH1IP6K3IP6K2 | |
| SCHEMBL30507140 | 0.86 | HTR7 (0.40) | IP6K1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL25318150 | 0.86 | HTR7 (0.40) | IP6K1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL30507360 | 0.83 | IP6K1 (0.61) | IP6K1IP6K3IP6K2HTR1AHTR2A | |
| SCHEMBL25316705 | 0.83 | IP6K1 (0.61) | IP6K1IP6K3IP6K2HTR1AHTR2A | |
| SCHEMBL30506835 | 0.82 | HTR1A (0.44) | IP6K1IP6K3IP6K2HTR1AHTR2A | |
| SCHEMBL25315499 | 0.82 | HTR1A (0.44) | IP6K1IP6K3IP6K2HTR1AHTR2A | |
| SCHEMBL25316240 | 0.82 | IP6K1 (0.63) | IP6K1IP6K3IP6K2HTR1AHTR2A | |
| SCHEMBL30507031 | 0.82 | IP6K1 (0.63) | IP6K1IP6K3IP6K2HTR1AHTR2A | |
| SCHEMBL25317326 | 0.82 | HTR7 (0.44) | IP6K1HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |