Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357395 | 0.82 | CYP1A2 (0.48) | ALDH1A1TSHRPTPN1CYP1A2CYP2C9 | |
| SCHEMBL25930137 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRPTPN1CYP1A2NR1H2 | |
| SCHEMBL542694 | 0.78 | NR1H3 (0.63) | ALDH1A1TSHRNR1H2NR1H3 | |
| SCHEMBL13219505 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRPTPN1CYP1A2NR1H2 | |
| SCHEMBL5865852 | 0.78 | TSHR (0.52) | ALDH1A1TSHRPTPN1CYP1A2NR1H2 | |
| SCHEMBL24425452 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2864482 | 0.78 | NR1H3 (0.57) | ALDH1A1TSHRPTPN1NR1H2NR1H3 | |
| SCHEMBL9548120 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRPTPN1CYP1A2NR1H2 | |
| SCHEMBL536228 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRPTPN1CYP1A2NR1H2 | |
| Water SCHEMBL29107396 | 0.76 | NR1H3 (0.61) | ALDH1A1TSHRNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933703-A | Fluorine-containing polyimide resin, preparation method and application thereof, biomass material-based electric power insulation rope and preparation method thereof | 国网安徽省电力有限公司电力科学研究院 | 2022-08-23 | — | — | CN | claimed |
| CN-112321828-A | Bio-based fluorine-containing polyimide resin, preparation method thereof and polyimide film | 合肥利夫生物科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| US-20230227797-A1 | TRANSAMINASE MUTANT AND USE THEREOF | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227797-A1 | TRANSAMINASE MUTANT AND USE THEREOF | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20220363662-A1 | COMPOUNDS AS LXR AGONISTS | Integral Biosciences Privated Limited (IN) | 2022-11-17 | — | — | US | disclosed |
| WO-2022224166-A1 | COMPOUNDS AS LXR AGONISTS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-10-27 | — | — | WO | disclosed |
| CN-114933703-A | Fluorine-containing polyimide resin, preparation method and application thereof, biomass material-based electric power insulation rope and preparation method thereof | 国网安徽省电力有限公司电力科学研究院 | 2022-08-23 | — | — | CN | disclosed |
| CN-112321828-A | Bio-based fluorine-containing polyimide resin, preparation method thereof and polyimide film | 合肥利夫生物科技有限公司 | 2021-02-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220363662-A1 | COMPOUNDS AS LXR AGONISTS | NR1H2, NR1H3, NR1H4 | ALDH1A1 781/4885TSHR 589/4885PTPN1 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.