SCHEMBL25930829

SCHEMBL25930829

CC1(C)OB(c2c(Cl)sc3ccccc23)OC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPL P06858 6/20 0.38
LIPG Q9Y5X9 6/20 0.38
GPR3 P46089 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.34
MCL1 Q07820 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ANPEP P15144 1/20 0.31
LAP3 P28838 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
HDAC1 Q13547 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30311829 1.00 LPL (0.38) LPLLIPGGPR3LOXL2MCL1
SCHEMBL23330795 0.82 LPL (0.39) LPLLIPGGPR3ANPEPLAP3
SCHEMBL29501282 0.81 LOXL2 (0.41) LPLLIPGGPR3LOXL2MCL1
SCHEMBL28995891 0.81 LOXL2 (0.41) LPLLIPGGPR3LOXL2MCL1
SCHEMBL22303408 0.77 LOXL2 (0.33) LPLLIPGGPR3LOXL2MCL1
SCHEMBL22310925 0.77 LOXL2 (0.33) LPLLIPGGPR3LOXL2MCL1
SCHEMBL22309993 0.77 TNKS (0.35) LPLLIPGGPR3LOXL2MCL1
SCHEMBL24702920 0.77 SNCA (0.46) KDM4EALDH1A1
SCHEMBL594378 0.75 LPL (0.39) LPLLIPGGPR3ANPEPLAP3
SCHEMBL2018549 0.74 LPL (0.50) LPLLIPGANPEPLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138254-A1 HETEROCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ELEMENT 上海八亿时空先进材料有限公司 2023-07-27 WO disclosed
CN-115867555-A Novel compound and organic light emitting device comprising same 株式会社LG化学 2023-03-28 CN disclosed
WO-2022059923-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-03-24 WO disclosed