Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25929004 | 0.84 | MTOR (0.34) | PIK3CAMTORGAKMAPK1 | |
| SCHEMBL29208999 | 0.78 | PIK3CA (0.43) | KDM4ETSHRHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL29209033 | 0.78 | PIK3CA (0.43) | KDM4ETSHRHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL29209035 | 0.78 | PIK3CA (0.43) | KDM4ETSHRHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL25930863 | 0.78 | KDM4E (0.40) | KDM4ETSHRHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL25930953 | 0.78 | KDM4E (0.40) | KDM4ETSHRHSD17B10NPSR1ALDH1A1 | |
| SCHEMBL17128116 | 0.77 | HDAC6 (0.43) | KDM4EGAAKMT2AHTTALOX15 | |
| SCHEMBL20796706 | 0.77 | HDAC6 (0.43) | KDM4EGAAKMT2AHTTALOX15 | |
| SCHEMBL20796804 | 0.77 | HDAC6 (0.43) | KDM4EGAAKMT2AHTTALOX15 | |
| SCHEMBL2556014 | 0.77 | HDAC6 (0.43) | KDM4EGAAKMT2AHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |