Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 11/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25930955 | 0.84 | KDM4E (0.38) | MTORPIK3CAMAPK1GAK | |
| SCHEMBL25929001 | 0.78 | OPRK1 (0.40) | MTOR | |
| SCHEMBL22733710 | 0.76 | MTOR (0.38) | MTORPIK3CA | |
| SCHEMBL29953774 | 0.75 | ALDH1A1 (0.40) | PIK3CAMAPK1GAK | |
| SCHEMBL1708576 | 0.75 | ALDH1A1 (0.40) | MTORPIK3CAMAPK1KHK | |
| SCHEMBL12419405 | 0.75 | DHODH (0.43) | MAPK1 | |
| Hydrochloric Acid SCHEMBL29951158 | 0.74 | ALDH1A1 (0.40) | MTORPIK3CAMAPK1KHK | |
| SCHEMBL25184755 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL30376783 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL18128074 | 0.68 | MTOR (0.31) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |