Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832315 | 0.87 | KDM4E (0.55) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL17938487 | 0.86 | CYP4F2 (0.54) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL23844744 | 0.86 | KDM4E (0.54) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL31509765 | 0.86 | KDM4E (0.54) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL23845061 | 0.86 | TSHR (0.48) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL17938461 | 0.85 | DGKA (0.56) | CYP4F2CYP4A11TSHRALDH1A1LMNA | |
| SCHEMBL17938493 | 0.85 | DGKA (0.56) | CYP4F2CYP4A11TSHRALDH1A1LMNA | |
| SCHEMBL23844771 | 0.83 | MAPT (0.47) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL17938453 | 0.81 | L3MBTL1 (0.55) | CYP4F2CYP4A11TSHRCYP3A4MAPK1 | |
| SCHEMBL10623418 | 0.81 | CYP4F2 (0.52) | CYP4F2CYP4A11DGKAL3MBTL1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718637-B2 | Prodrugs of 4′-C-substituted-2-halo-2′- deoxyadenosine nucleosides and methods of making and using the same | GILEAD SCIENCES, INC. (US) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718637-B2 | Prodrugs of 4′-C-substituted-2-halo-2′- deoxyadenosine nucleosides and methods of making and using the same | DCTD, MTAP, ADA | CYP4F2 1421/4885CYP4A11 1973/4885TSHR 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.