Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 2/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.33 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31217358 | 0.87 | GBA1 (0.56) | GBA1JAK2JAK1JAK3SMN1; SMN2 | |
| SCHEMBL14241412 | 0.81 | SMN1; SMN2 (0.47) | GBA1JAK2JAK1TSHRJAK3 | |
| SCHEMBL25933021 | 0.76 | LPL (0.36) | IDO1SMN1; SMN2LMNA | |
| SCHEMBL23932182 | 0.76 | MKNK1 (0.36) | IDO1CRHR1 | |
| SCHEMBL18111217 | 0.70 | IDO1 (0.39) | IDO1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL17316578 | 0.69 | GBA1 (1.00) | GBA1SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL20797487 | 0.69 | ALDH1A1 (0.40) | GBA1JAK2JAK3SMN1; SMN2LMNA | |
| SCHEMBL31217376 | 0.69 | GBA1 (0.63) | GBA1SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL17316407 | 0.68 | GBA1 (0.50) | GBA1JAK2JAK1JAK3SMN1; SMN2 | |
| SCHEMBL24707519 | 0.68 | GBA1 (0.39) | GBA1TSHRSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131271-A1 | PYRROLE FUSED-RING PYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2023-07-13 | — | — | WO | disclosed |