SCHEMBL25933434

SCHEMBL25933434

CC(C)(C)OC(=O)N1CCC(CN2CCN(c3ccc(C4CCN(c5ccc(C#N)c(C(F)(F)F)c5)CC4)cc3)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 16/20 0.47
GPR119 Q8TDV5 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30493253 1.00 AR (0.47) ARGPR119
SCHEMBL25437610 0.98 AR (0.46) ARGPR119
SCHEMBL25934240 0.91 AR (0.49) ARGPR119
SCHEMBL25439632 0.88 AR (0.47) AR
SCHEMBL25929486 0.85 GPR119 (0.51) ARGPR119
SCHEMBL25935905 0.85 AR (0.47) ARGPR119
SCHEMBL25930392 0.85 GPR119 (0.53) ARGPR119
SCHEMBL25934165 0.84 AR (0.50) AR
SCHEMBL25933822 0.84 AR (0.47) AR
SCHEMBL25233436 0.83 AR (0.46) ARGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139199-A1 COMPOUNDS AND THEIR USE IN TREATING CANCER ASTRAZENECA AB (SE) 2023-07-27 WO disclosed