Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411553 | 0.93 | HTT (0.41) | HTTBACE1ELANEMAPTALDH1A1 | |
| SCHEMBL24440831 | 0.92 | BACE1 (0.44) | HTTBACE1ELANEMAPTALDH1A1 | |
| SCHEMBL21400894 | 0.91 | FGFR1 (0.44) | ALOX15HTTFGFR1VCPELANE | |
| SCHEMBL19187389 | 0.90 | ALOX15 (0.40) | ALOX15HTTBACE1FGFR1VCP | |
| SCHEMBL19623182 | 0.90 | BACE1 (0.41) | HTTBACE1ELANEMAPTKDM4E | |
| SCHEMBL24180747 | 0.89 | ALOX15 (0.46) | ALOX15FGFR1VCPELANEMAPT | |
| SCHEMBL18308840 | 0.87 | BACE1 (0.47) | HTTBACE1ELANEMAPTALDH1A1 | |
| SCHEMBL17625853 | 0.85 | ELANE (0.47) | BACE1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL24170583 | 0.84 | ELANE (0.42) | ALOX15BACE1ELANEMAPTKDM4E | |
| SCHEMBL24158061 | 0.84 | PRKCZ (0.38) | FGFR1MAPTRXFP1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056667-B1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-08-02 | — | — | EP | disclosed |