SCHEMBL25933765

SCHEMBL25933765

CC(O)c1cc(C(=O)O)ccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 11/20 0.53
KDM5B Q9UGL1 7/20 0.53
KDM5C P41229 6/20 0.53
KDM4A O75164 6/20 0.53
KDM5A P29375 6/20 0.53
KDM4E B2RXH2 4/20 0.53
KDM2A Q9Y2K7 4/20 0.53
KDM3A Q9Y4C1 4/20 0.53
KDM6B O15054 3/20 0.53
TET3 O43151 1/20 0.53
BBOX1 O75936 1/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
ASPH Q12797 1/20 0.53
KDM4D Q6B0I6 1/20 0.53
TET2 Q6N021 1/20 0.53
ALKBH5 Q6P6C2 1/20 0.53
KDM7A Q6ZMT4 1/20 0.53
KDM8 Q8N371 1/20 0.53
TET1 Q8NFU7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759894 0.87 KDM4C (0.55) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL17545205 0.85 GABRP (0.56) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL6637819 0.85 MEN1 (0.39) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL23583774 0.85 KDM4C (0.57) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL25709497 0.84 KDM4C (0.52) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL6926193 0.84 KDM5C (0.43) KDM4CKDM5BKDM5CKDM5AGABRP
SCHEMBL26910686 0.81 KDM4C (0.49) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL25342268 0.81 KDM4C (0.49) KDM4CKDM5BKDM5CKDM4AKDM5A
SCHEMBL25933766 0.81 KDM4E (0.55) KDM4CKDM5BKDM5CKDM5AKDM4E
SCHEMBL25933767 0.81 KDM5B (0.49) KDM4CKDM5BKDM5CKDM4AKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 KDM4C 4120/4885KDM5B 3550/4885KDM5C 3864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.