Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.49 |
| ▸ | KDM5A | P29375 | 8/20 | 0.49 |
| ▸ | KDM5C | P41229 | 5/20 | 0.49 |
| ▸ | KDM6B | O15054 | 4/20 | 0.49 |
| ▸ | KDM4A | O75164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ASPH | Q12797 | 1/20 | 0.49 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054683 | 0.85 | KDM4C (0.50) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL24213992 | 0.83 | KDM4E (0.51) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL14836839 | 0.82 | KDM4C (0.47) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL25933765 | 0.81 | KDM4C (0.53) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL23583774 | 0.80 | KDM4C (0.57) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL1759894 | 0.79 | KDM4C (0.55) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL5358458 | 0.78 | KDM4C (0.46) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL19705976 | 0.78 | KDM4C (0.46) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL17545205 | 0.77 | GABRP (0.56) | KDM5BKDM4CKDM5AKDM5CKDM6B | |
| SCHEMBL25709497 | 0.76 | KDM4C (0.52) | KDM5BKDM4CKDM5AKDM5CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
| WO-2022015977-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | KDM5B 3550/4885KDM4C 4120/4885KDM5A 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.