Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 9/20 | 0.45 |
| ▸ | HRH1 | P35367 | 9/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493265 | 1.00 | HRH2 (0.45) | HRH2HRH1EPHX2HRH3NSD2 | |
| SCHEMBL30493283 | 0.91 | HRH2 (0.45) | HRH2HRH1EPHX2HRH3NSD2 | |
| SCHEMBL30493223 | 0.89 | HRH2 (0.43) | HRH2HRH1EPHX2HRH3RET | |
| SCHEMBL25933822 | 0.85 | AR (0.47) | RETKCNH2 | |
| SCHEMBL25933930 | 0.82 | HRH3 (0.51) | HRH2HRH1HRH3CYP3A4CYP2C9 | |
| SCHEMBL30493235 | 0.79 | AR (0.43) | NSD2EHMT2RETGPR119 | |
| SCHEMBL25330446 | 0.79 | AR (0.43) | NSD2EHMT2RETGPR119 | |
| SCHEMBL23703842 | 0.79 | ALDH1A1 (0.52) | RETKCNH2GPR119 | |
| SCHEMBL25929486 | 0.79 | GPR119 (0.51) | RETGPR119 | |
| SCHEMBL30493231 | 0.77 | AR (0.45) | EPHX2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |