Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | PLAT | P00750 | 4/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919952 | 0.78 | SLC18A3 (0.38) | HTR2CPLATMAPK13MAPK9MAPK12 | |
| SCHEMBL2755237 | 0.72 | HTR2C (0.54) | HTR2CPLATMAPK13MAPK9MAPK12 | |
| SCHEMBL18814355 | 0.71 | HTR2C (0.37) | HTR2CMAPK13MAPK9MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL237629 | 0.71 | HTR2C (0.55) | HTR2CPLATMAPK13MAPK9MAPK12 | |
| SCHEMBL19410765 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL2755233 | 0.70 | HTR2C (0.52) | HTR2CPLAT | |
| Hydrochloric Acid SCHEMBL2902954 | 0.69 | HTR2C (0.39) | HTR2CMAPK13MAPK9MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL239345 | 0.69 | HTR2C (0.54) | HTR2CPLAT | |
| SCHEMBL13093276 | 0.68 | — | — | |
| SCHEMBL28239703 | 0.68 | ADORA2A (0.33) | HTR2CMAPK13MAPK9MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |