Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22191429 | 0.85 | GAA (0.52) | GAAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25934308 | 0.80 | VNN1 (0.52) | GAAKDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19145368 | 0.79 | VNN1 (0.57) | GAAALDH1A1HPGDVNN1 | |
| SCHEMBL25934345 | 0.78 | VNN1 (0.57) | GAAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL171575 | 0.77 | HTT (0.62) | GAAKDM4EALDH1A1HPGDNTRK1 | |
| SCHEMBL15584259 | 0.77 | NTRK1 (0.52) | NTRK1CLK4APPPAK4AURKA | |
| SCHEMBL4951737 | 0.75 | MAPT (0.59) | GAAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18512064 | 0.74 | VNN1 (0.53) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13879797 | 0.74 | SMN1; SMN2 (0.44) | KDM4ENTRK1MAPTKDM5AKDM4C | |
| SCHEMBL6692696 | 0.73 | FFAR1 (0.67) | ALDH1A1HPGDAPPMAPTKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234935-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234935-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | PACSIN2, MAP3K20, PHKG1 | GAA 631/4885KDM4E 2270/4885ALDH1A1 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.