Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528794 | 0.78 | ESR2 (0.74) | ESR2ABHD6NR1H2DDB1CRBN | |
| SCHEMBL587847 | 0.78 | ESR2 (0.74) | ESR2ABHD6NR1H2DDB1CRBN | |
| SCHEMBL25322440 | 0.77 | HPGD (0.38) | NR1H2PDK2 | |
| SCHEMBL30644260 | 0.76 | ABHD6 (0.45) | ESR2ABHD6NR1H2DDB1CRBN | |
| SCHEMBL31510697 | 0.76 | HPGD (0.40) | NR1H2PDK2 | |
| SCHEMBL1263942 | 0.75 | ESR2 (0.61) | ESR2ABHD6NR1H2RORCHDAC1 | |
| SCHEMBL29407443 | 0.74 | ESR2 (0.46) | ESR2ABHD6NR1H2DDB1CRBN | |
| SCHEMBL22981885 | 0.74 | ESR2 (0.46) | ESR2ABHD6NR1H2DDB1CRBN | |
| SCHEMBL1263385 | 0.73 | ESR2 (0.63) | ESR2ABHD6NR1H2DDB1CRBN | |
| SCHEMBL30014804 | 0.73 | ESR2 (0.47) | ESR2ABHD6NR1H2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |