Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.74 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.64 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587847 | 1.00 | ESR2 (0.74) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL29587073 | 0.95 | NR1H2 (0.72) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL1011003 | 0.95 | NR1H2 (0.72) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL38653092 | 0.93 | NR1H2 (0.70) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL1263385 | 0.92 | ESR2 (0.63) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL1263942 | 0.92 | ESR2 (0.61) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL30951607 | 0.89 | ABHD6 (0.60) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL330056 | 0.89 | ABHD6 (0.60) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL31345278 | 0.88 | ESR2 (0.57) | ESR2NR1H2ABHD6HDAC1HDAC6 | |
| SCHEMBL24265586 | 0.87 | NR1H2 (0.62) | ESR2NR1H2ABHD6HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829545-B | Substituted pyrazolylpiperidine carboxylic acids | 拜耳公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| CN-119954773-A | PSMA compounds, pharmaceutical compositions comprising the same and uses thereof | 苏州威智创科生物有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-111819175-B | Broad-spectrum antiviral compositions and methods | 艾弗里斯生物有限责任公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119698422-A | Aza condensed ring compound, preparation method and medical application thereof | 苏州爱科百发生物医药技术有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119365479-A | Conjugates comprising Toll-like receptor agonists | 慕宝盛科生物医药(上海)有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119053600-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| CN-118556059-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112004816-B | PRC2 inhibitors | 米拉蒂医疗股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116829545-A | Substituted pyrazolylpiperidine carboxylic acids | 拜耳公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116789641-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2023-09-22 | — | — | CN | disclosed |
| CN-115551831-A | CYP11A1 inhibitor | 奥赖恩公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | disclosed |
| CN-109863145-B | Novel tetrahydroisoquinoline and tetrahydronaphthyridine compounds for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114269748-A | Imidazo [1,2-c ] pyrimidine derivatives as PRC2 inhibitors for the treatment of cancer | 米拉蒂医疗股份有限公司 | 2022-04-01 | — | — | CN | disclosed |