SCHEMBL25936

SCHEMBL25936

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.75
ADORA1 P30542 2/20 0.75
MEN1 O00255 2/20 0.75
KMT2A Q03164 2/20 0.75
PI4KA P42356 2/20 0.75
PI4K2B Q8TCG2 2/20 0.75
PI4K2A Q9BTU6 2/20 0.75
PI4KB Q9UBF8 2/20 0.75
DPP4 P27487 1/20 0.75
SLC28A1 O00337 1/20 0.75
MAP3K7 O43318 1/20 0.75
SLC28A2 O43868 1/20 0.75
GAPDH P04406 1/20 0.75
MAPK1 P28482 1/20 0.75
ADORA2A P29274 1/20 0.75
ADORA2B P29275 1/20 0.75
STAT6 P42226 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
DOT1L Q8TEK3 1/20 0.75
SLC29A1 Q99808 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29388656 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL12746919 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL29941460 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL23050294 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL12031327 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL24538798 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL2550330 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL12150808 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL25937 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL16359957 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4641 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139251-A1 RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-05-21 US claimed
WO-2026102302-A1 POLYNUCLEOTIDES CONTAINING A MODIFIED 3'-REGION MODERNATX, INC. (US) 2026-05-15 WO claimed
US-20260132406-A1 RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kinase 7 (ALK7), Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-05-14 US claimed
EP-4739343-A2 CIRCULAR RNA VACCINES FOR SEASONAL FLU AND METHODS OF USES Shanghai Circode Biomed Co., Ltd (CN) 2026-05-13 EP claimed
EP-4731229-A1 SIRNA, CONJUGATE WHICH CONTAIN SIRNA, PHARMACEUTICAL COMPOSITION AND USES THEREOF Hansoh Bio LLC (US) 2026-04-29 EP claimed
US-20260092276-A1 Carbohydrate-oligonucleotide conjugates, pharmaceutical compositions, and therapeutic applications KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2026-04-02 US claimed
US-12582668-B2 Methods for the treatment of alpha-1 antitrypsin deficiency (AATD) Arrowhead Pharmaceuticals, Inc. (US) 2026-03-24 US claimed
US-20260078375-A1 RNAi Agents for Inhibiting Influenza A Viral Gene Expression, Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-03-19 US claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
EP-1313752-A2 METHODS FOR SYNTHESIZING NUCLEOSIDES, NUCLEOSIDE DERIVATIVES AND NON-NUCLEOSIDE DERIVATIVES RIBOZYME PHARMACEUTICALS, INC. (US) 2003-05-28 EP claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
US-20020120129-A1 Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives RIBOZYME PHARMACEUTICALS, INC. 2002-08-29 US claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 WO claimed
WO-2002018405-A2 METHODS FOR SYNTHESIZING NUCLEOSIDES, NUCLEOSIDE DERIVATIVES AND NON-NUCLEOSIDE DERIVATIVES RIBOZYME PHARMACEUTICALS, INCORPORATED (US) 2002-03-07 WO claimed
EP-1108724-A2 Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules RIBOZYME PHARMACEUTICALS, INC. (US) 2001-06-20 EP claimed
US-5962675-A Chemical syntheses of 2'-O-methoxy purine nucleosides RIBOZYME PHARMACEUTICALS, INC. (US) 1999-10-05 US claimed
US-5767270-A PROTECTING EXOCYCLIC AMINO GROUPS ISIS PHARMACEUTICALS, INC. (US) 1998-06-16 US claimed
CN-1147815-A Adenosine derivatives SANDOZ LTD (CH) 1997-04-16 CN claimed
WO-1996041812-A1 OLIGONUCLEOTIDE PHOSPHORYLATION METHOD AND PRODUCTS ISIS INNOVATION LIMITED (GB) 1996-12-27 WO claimed