SCHEMBL29388656

SCHEMBL29388656

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.75
ADORA1 P30542 2/20 0.75
MEN1 O00255 2/20 0.75
KMT2A Q03164 2/20 0.75
PI4KA P42356 2/20 0.75
PI4K2B Q8TCG2 2/20 0.75
PI4K2A Q9BTU6 2/20 0.75
PI4KB Q9UBF8 2/20 0.75
DPP4 P27487 1/20 0.75
SLC28A1 O00337 1/20 0.75
MAP3K7 O43318 1/20 0.75
SLC28A2 O43868 1/20 0.75
GAPDH P04406 1/20 0.75
MAPK1 P28482 1/20 0.75
ADORA2A P29274 1/20 0.75
ADORA2B P29275 1/20 0.75
STAT6 P42226 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
DOT1L Q8TEK3 1/20 0.75
SLC29A1 Q99808 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12746919 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL25936 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL29941460 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL23050294 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL12031327 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL24538798 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL2550330 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL12150808 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL25937 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA
SCHEMBL16359957 1.00 ADORA3 (0.75) ADORA3ADORA1MEN1KMT2API4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 861 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095093-A RNAi agents for inhibiting expression of inhibin subunit beta E (INHBE), pharmaceutical compositions and methods of use 2026-05-26 CN claimed
EP-3688173-B1 IN VITRO METHOD OF MRNA DELIVERY USING LIPID NANOPARTICLES INTELLIA THERAPEUTICS INC (US) 2025-12-17 EP claimed
US-20250325702-A1 COMPOSITIONS AND METHODS FOR EDITING A TRANSTHYRETIN GENE BEAM THERAPEUTICS INC. (US) 2025-10-23 US claimed
EP-4615425-A1 BASE EDITING OF TRANSTHYRETIN GENE Beam Therapeutics Inc. (US) 2025-09-17 EP claimed
WO-2025109169-A1 IMPROVED METHOD FOR IDENTIFICATION OF NUCLEOTIDE MODIFICATIONS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-05-30 WO claimed
CN-120077136-A SiRNA and drug for inhibiting Amyloid Precursor Protein (APP) gene expression and application thereof 广州必贝特医药股份有限公司 2025-05-30 CN claimed
WO-2025103457-A1 SIRNA FOR INHIBITING LPA EXPRESSION AND USE THEREOF 纳肽得(青岛)生物医药有限公司 2025-05-22 WO claimed
WO-2025103453-A1 SIRNA FOR INHIBITING ANGIOTENSINOGEN EXPRESSION AND USE THEREOF 纳肽得(青岛)生物医药有限公司 2025-05-22 WO claimed
CN-120020252-A SiRNA for inhibiting LPA expression and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-20 CN claimed
CN-120005876-A SiRNA for inhibiting expression of angiotensinogen and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-16 CN claimed
CN-114076805-B Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-07-26 CN claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
WO-2022109129-A1 CONJUGATES OF S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS HAVING ENHANCED LIVER TARGETING ALIGOS THERAPEUTICS, INC. (US) 2022-05-27 WO claimed
CN-114555188-A Methods of treating diseases and disorders associated with APOC3 箭头药业股份有限公司 2022-05-27 CN claimed
WO-2022104001-A1 EXPANDED PROTEIN LIBRARIES AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2022-05-19 WO claimed
WO-2022104366-A1 CHEMICAL MODIFICATIONS FOR INHIBITING EXPRESSION OF ALDH2 DICERNA PHARMACEUTICALS, INC. (US) 2022-05-19 WO claimed
CN-114502204-A RNA combinations and compositions with reduced immunostimulatory properties 库尔维科公司 2022-05-13 CN claimed
US-20220125825-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. 2022-04-28 US claimed
WO-2022087011-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2022-04-28 WO claimed
WO-2022081758-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2022-04-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220125825-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS RNGTT, PHAX, HAVCR2 ADORA3 1372/4885ADORA1 1419/4885MEN1 4660/4885
US-20250325702-A1 COMPOSITIONS AND METHODS FOR EDITING A TRANSTHYRETIN GENE TTR, TTN, HTT ADORA3 4450/4885ADORA1 4497/4885MEN1 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.