Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061723 | 0.86 | MGLL (0.44) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL25935913 | 0.72 | TDP1 (0.48) | — | |
| SCHEMBL23889659 | 0.72 | DRD2 (0.49) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL18100026 | 0.70 | MGLL (0.44) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL22698762 | 0.70 | MGLL (0.41) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL16834889 | 0.69 | PTGS1 (0.47) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL22220046 | 0.68 | MGLL (0.41) | OPRM1OPRD1OPRK1PTGS1PTGS2 | |
| SCHEMBL12301862 | 0.67 | MGLL (0.54) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL20730324 | 0.67 | EPHX1 (0.41) | LMNAHPGDHTTSMN1; SMN2NPSR1 | |
| SCHEMBL31087102 | 0.67 | CHRM2 (0.53) | PTGS1PTGS2CHRM2MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147328-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION WITH HYDOLYSABLE MALEIMIDE LINKERS AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |