Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.49 |
| ▸ | YAP1 | P46937 | 3/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195218 | 0.94 | NAMPT (0.57) | NAMPTPRMT5YAP1GPR119TNK2 | |
| SCHEMBL31009246 | 0.84 | PDK4 (0.52) | NAMPTYAP1GPR119TNK2GRM5 | |
| SCHEMBL1366854 | 0.84 | PDK4 (0.52) | NAMPTYAP1GPR119TNK2GRM5 | |
| SCHEMBL23249954 | 0.82 | NAMPT (0.50) | NAMPTPRMT5YAP1GPR119TNK2 | |
| SCHEMBL23411387 | 0.82 | NAMPT (0.52) | NAMPTGPR119TNK2GRM5GRM1 | |
| SCHEMBL29505171 | 0.81 | CYP11B2 (0.53) | NAMPTGPR119TNK2GRM5GRM1 | |
| SCHEMBL4006887 | 0.81 | GRM1 (0.56) | PRMT5GPR119TNK2GRM5GRM1 | |
| SCHEMBL30913564 | 0.81 | GRM1 (0.56) | PRMT5GPR119TNK2GRM5GRM1 | |
| SCHEMBL31510790 | 0.81 | NAMPT (0.52) | NAMPTGPR119TNK2GRM5GRM1 | |
| SCHEMBL749505 | 0.80 | PPARG (0.47) | NAMPTGPR119TNK2GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |