Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 9/20 | 0.56 |
| ▸ | GRM5 | P41594 | 8/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006887 | 1.00 | GRM1 (0.56) | GRM1GRM5PRMT5WNT3AGPR119 | |
| SCHEMBL8195218 | 0.87 | NAMPT (0.57) | GRM1GRM5PRMT5GPR119PDK4 | |
| SCHEMBL30899634 | 0.83 | GRM1 (0.52) | GRM1GRM5WNT3AGPR119PDK4 | |
| SCHEMBL30366121 | 0.83 | GRM1 (0.52) | GRM1GRM5WNT3AGPR119PDK4 | |
| SCHEMBL29505171 | 0.83 | CYP11B2 (0.53) | GRM1GRM5WNT3AGPR119PDK4 | |
| SCHEMBL25143682 | 0.82 | WNT3A (0.48) | GRM1GRM5PRMT5WNT3AGPR119 | |
| SCHEMBL30201557 | 0.82 | WNT3A (0.48) | GRM1GRM5PRMT5WNT3AGPR119 | |
| SCHEMBL15146264 | 0.82 | GRM1 (0.56) | GRM1GRM5PRMT5WNT3AGPR119 | |
| SCHEMBL29518255 | 0.82 | GRM1 (0.56) | GRM1GRM5PRMT5WNT3AGPR119 | |
| SCHEMBL903903 | 0.82 | GRM1 (0.56) | GRM1GRM5WNT3AGPR119PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |