Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24307263 | 0.73 | MMP12 (0.40) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL89103 | 0.72 | KDM4E (0.56) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL24307264 | 0.72 | MMP12 (0.40) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL8265565 | 0.71 | MMP12 (0.50) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL13090980 | 0.70 | MMP12 (0.53) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL24307261 | 0.68 | MMP12 (0.50) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL24306751 | 0.68 | MMP12 (0.50) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL26766724 | 0.68 | MMP12 (0.50) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL26766745 | 0.68 | MMP12 (0.50) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 | |
| SCHEMBL8627768 | 0.67 | NPC1 (0.50) | MMP12BRD4CREBBPALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219461-A1 | TETRAHYDROISOQUINOLINE DERIVATIVE AND USE THEREOF | Medshine Discovery Inc. (CN) | 2023-08-02 | — | — | EP | disclosed |