Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671163 | 0.88 | NPC1 (0.50) | NPC1MMP12MAPTKDM4EALDH1A1 | |
| SCHEMBL8629003 | 0.84 | NPC1 (0.49) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8634618 | 0.80 | NPC1 (0.46) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8630641 | 0.80 | MAPT (0.64) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8630183 | 0.80 | MAPT (0.64) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8634643 | 0.80 | MAPT (0.64) | NPC1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL89103 | 0.79 | KDM4E (0.56) | NPC1MMP12KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3932106 | 0.75 | MMP12 (0.44) | NPC1MMP12MAPTKDM4EALDH1A1 | |
| SCHEMBL8265565 | 0.74 | MMP12 (0.50) | NPC1MMP12MAPTKDM4EALDH1A1 | |
| SCHEMBL10619142 | 0.73 | MMP12 (0.43) | MMP12MAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824652-A | IMMUNOSTIMULANTS, ANTITUMOR AGENTS | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TECHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1998-10-20 | — | — | US | disclosed |
| EP-0695308-B1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIV LJUBLJANI (SI) | 1998-07-01 | — | — | EP | disclosed |
| EP-0695308-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024152-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1994-10-27 | — | — | WO | disclosed |