Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | LCK | P06239 | 6/20 | 0.43 |
| ▸ | MET | P08581 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937403 | 0.86 | KCNQ2 (0.41) | KDRLCKMETMEN1KMT2A | |
| SCHEMBL25428783 | 0.86 | KDR (0.46) | KDRLCKMETTHRBMEN1 | |
| SCHEMBL25937424 | 0.84 | NOTUM (0.53) | THRBTP53MAPTSIGMAR1 | |
| SCHEMBL27983431 | 0.83 | MAPT (0.41) | MAPTUSP30 | |
| SCHEMBL30557580 | 0.80 | KCNQ2 (0.46) | MEN1KMT2ARIPK1USP30SIGMAR1 | |
| SCHEMBL25937545 | 0.80 | KCNQ2 (0.46) | MEN1KMT2ARIPK1USP30SIGMAR1 | |
| SCHEMBL25937840 | 0.80 | SLC22A12 (0.41) | MEN1KMT2ARIPK1USP30SIGMAR1 | |
| SCHEMBL25937866 | 0.79 | TP53 (0.40) | TP53MAPTSIGMAR1 | |
| SCHEMBL25937783 | 0.79 | KDR (0.48) | KDRLCKMETTHRBMEN1 | |
| SCHEMBL25937457 | 0.78 | GRM7 (0.47) | THRBTP53MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |