Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25993185 | 0.85 | METAP1 (0.34) | — | |
| SCHEMBL25937879 | 0.77 | PDK2 (0.34) | — | |
| SCHEMBL27118055 | 0.77 | METAP1 (0.35) | — | |
| SCHEMBL26021101 | 0.76 | — | — | |
| SCHEMBL27120133 | 0.76 | SIGMAR1 (0.32) | — | |
| SCHEMBL27122537 | 0.76 | SIGMAR1 (0.32) | — | |
| SCHEMBL27020519 | 0.75 | SIGMAR1 (0.32) | — | |
| SCHEMBL26022379 | 0.75 | METAP1 (0.33) | — | |
| SCHEMBL27020815 | 0.73 | SLC6A2 (0.30) | — | |
| SCHEMBL25997197 | 0.71 | METAP1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820574-B1 | 3-(5-AMINO-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF IKAROS FAMILY ZINC FINGER 2 (IKZF2)-DEPENDENT DISEASES | NOVARTIS AG (CH) | 2023-08-09 | — | — | EP | disclosed |