Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.51 |
| ▸ | PLK1 | P53350 | 2/20 | 0.48 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.44 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.44 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.44 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.44 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.44 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.44 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.44 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137550 | 0.85 | HTR7 (0.50) | HTR7FDPSADRA1DHTR2CADRA1A | |
| SCHEMBL24137805 | 0.83 | HTR7 (0.60) | HTR7FDPSADRA1DHTR2CADRA1A | |
| SCHEMBL19237093 | 0.80 | TTK (0.52) | HTR7FDPSADRA1DHTR2CADRA1A | |
| SCHEMBL24137863 | 0.78 | CDK7 (0.46) | HTR7FDPSADRA1DHTR2CADRA1A | |
| SCHEMBL24137867 | 0.77 | HTR7 (0.47) | HTR7FDPSADRA1DHTR2CADRA1A | |
| SCHEMBL11520815 | 0.76 | NPSR1 (0.55) | HTR7PLK1PLK2CAMK2DKDM4E | |
| SCHEMBL30596236 | 0.75 | HTR7 (0.48) | HTR7CAMK2DADRA1DHTR2CADRA1A | |
| SCHEMBL19237111 | 0.75 | MAPT (0.50) | HTR7PLK1ADRA1DHTR2CADRA1A | |
| SCHEMBL24137504 | 0.75 | HTR7 (0.48) | HTR7CAMK2DADRA1DHTR2CADRA1A | |
| SCHEMBL22191728 | 0.75 | CCNC (0.46) | HTR7CAMK2DFDPSADRA1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234935-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234935-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | PACSIN2, MAP3K20, PHKG1 | HTR7 2493/4885PLK1 64/4885PLK2 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.