Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 6/20 | 0.45 |
| ▸ | JAK2 | O60674 | 5/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.38 |
| ▸ | WNT1 | P04628 | 4/20 | 0.38 |
| ▸ | CLK2 | P49760 | 5/20 | 0.38 |
| ▸ | CLK3 | P49761 | 4/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137846 | 0.86 | CDK7 (0.52) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL25933938 | 0.79 | CDK7 (0.40) | CDK7CDK2DYRK1AWNT1CLK2 | |
| SCHEMBL24137841 | 0.79 | JAK2 (0.61) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL25933934 | 0.79 | CCNC (0.44) | CDK7JAK2CDK2DYRK1AWNT1 | |
| SCHEMBL24137560 | 0.78 | CDK2 (0.57) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL24137727 | 0.78 | JAK2 (0.52) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL25936076 | 0.78 | JAK2 (0.48) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL25936215 | 0.77 | JAK2 (0.50) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL24137915 | 0.74 | JAK2 (0.57) | CDK7JAK2AKT1CDK2DYRK1A | |
| SCHEMBL21318857 | 0.71 | JAK2 (0.56) | JAK2AKT1CDK2DYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234935-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234935-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | PACSIN2, MAP3K20, PHKG1 | CDK7 210/4885JAK2 228/4885PTGER2 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.