Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 14/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25945712 | 0.85 | MAP4K1 (0.46) | MAP4K1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL25939445 | 0.79 | MAP4K1 (0.45) | MAP4K1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL25938330 | 0.78 | MAP4K1 (0.56) | MAP4K1KDM4EALDH1A1PTGER3 | |
| SCHEMBL21702971 | 0.78 | MAP4K1 (0.55) | MAP4K1 | |
| SCHEMBL25938804 | 0.78 | MAP4K1 (0.43) | MAP4K1 | |
| SCHEMBL25938860 | 0.76 | MAP4K1 (0.47) | MAP4K1PTGER3 | |
| SCHEMBL25939411 | 0.76 | MAP4K1 (0.52) | MAP4K1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL25940462 | 0.76 | MAP4K1 (0.35) | MAP4K1KDM4EALDH1A1PTGER3 | |
| SCHEMBL21684527 | 0.75 | MAP4K1 (0.65) | MAP4K1 | |
| SCHEMBL21684525 | 0.75 | MAP4K1 (0.65) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |