Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703411 | 0.84 | MAP4K1 (0.44) | MAP4K1 | |
| SCHEMBL21703108 | 0.84 | MAP4K1 (0.44) | MAP4K1 | |
| SCHEMBL25938836 | 0.83 | MAP4K1 (0.43) | MAP4K1 | |
| SCHEMBL25952139 | 0.80 | ALDH1A1 (0.37) | MAP4K1 | |
| SCHEMBL25938828 | 0.79 | MAP4K1 (0.55) | MAP4K1 | |
| SCHEMBL21703395 | 0.79 | MAP4K1 (0.40) | MAP4K1 | |
| SCHEMBL25952289 | 0.79 | MAP4K1 (0.42) | MAP4K1 | |
| SCHEMBL25938330 | 0.78 | MAP4K1 (0.56) | MAP4K1 | |
| SCHEMBL25938485 | 0.78 | MAP4K1 (0.40) | MAP4K1 | |
| SCHEMBL25938860 | 0.77 | MAP4K1 (0.47) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |