Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 17/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938330 | 0.89 | MAP4K1 (0.56) | MAP4K1PTGER3PKMSMN1; SMN2 | |
| SCHEMBL25938898 | 0.81 | MAP4K1 (0.41) | MAP4K1PTGER3PKMSMN1; SMN2 | |
| SCHEMBL25950670 | 0.79 | MAP4K1 (0.45) | MAP4K1PTGER3PKMSMN1; SMN2 | |
| SCHEMBL25938916 | 0.78 | MAP4K1 (0.62) | MAP4K1 | |
| SCHEMBL25938804 | 0.77 | MAP4K1 (0.43) | MAP4K1 | |
| SCHEMBL25940521 | 0.77 | MAP4K1 (0.44) | MAP4K1PTGER3PKMSMN1; SMN2 | |
| SCHEMBL25938485 | 0.76 | MAP4K1 (0.40) | MAP4K1PTGER3 | |
| SCHEMBL21683880 | 0.75 | MAP4K1 (0.75) | MAP4K1 | |
| SCHEMBL21683873 | 0.75 | MAP4K1 (0.75) | MAP4K1 | |
| SCHEMBL21683877 | 0.75 | MAP4K1 (0.75) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |