Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938616 | 0.92 | KDM4E (0.44) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25949080 | 0.91 | ALOX5 (0.46) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25939053 | 0.88 | ALOX5 (0.46) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25948717 | 0.86 | KDM4E (0.56) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25938557 | 0.86 | KDM4E (0.52) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25938555 | 0.85 | RAD52 (0.48) | SMN1; SMN2KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL25941965 | 0.84 | KDM4E (0.58) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25938811 | 0.83 | PKM (0.41) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25938740 | 0.83 | HDAC1 (0.41) | SMN1; SMN2KDM4ELMNAALDH1A1GAA | |
| SCHEMBL25941962 | 0.82 | ALOX5 (0.59) | SMN1; SMN2KDM4ELMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |